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Vital Statistics
| Birthdate: 4/4/66 |
Birthplace: Brooklyn, NY, U.S.A. |
| Sex: Male |
Citizenship: U.S.A. |
Work Address |
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Molecular Biology Research Group |
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| Department of Chemistry and Biochemistry |
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| Texas State University | San Marcos |
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| 419 Centennial Hall |
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| 601 University Drive |
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| San Marcos, TX 78666 |
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| e-mail: sk13@txstate.edu |
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| Tel: (512) 245-0358 |
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| Fax: (512) 245-1922 |
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Education |
New York University |
Ph.D. |
1995 |
Biology |
| New York University |
M.S. |
1992 |
Biology |
| New York University |
M.Phil. |
1992 |
Biology |
| New York University |
B.A. |
1988 |
Biology |
Professional Experience |
2001-Present |
Associate Director, Xiphophorus Genetic Stock Center,
Texas State University | San Marcos, Department of Chemistry and Biochemistry,
San Marcos, TX. |
2000-Present |
Assistant Professor of Research, Texas
State University | San Marcos, Department of Chemistry and Biochemistry,
San Marcos, TX. |
2000 |
Assistant Professor, University of Texas, M.D. Anderson Cancer Center,
Science Park-Research
Division, Smithville, TX. |
1998-2000 |
Research Associate (a junior faculty position), University of Texas,
M.D. Anderson Cancer Center, Science
Park-Research Division, Smithville, TX. |
1997-1998 |
Project Investigator, University of Texas, M.D. Anderson Cancer Center,
Science Park-Research
Division, Smithville, TX. |
1995-1996 |
National Cancer Institute Post-Doctoral Training Fellow, University
of Texas, M.D. Anderson Cancer Center, Science
Park-Research Division, Smithville, TX. |
1992-1995 |
Adjunct Professor, Field Biology and Elements of Ecology, Department
of Biology, New York University,
New York, NY. |
1989-1993 |
Teaching Assistant, Department of Biology, New
York University, New York, NY. |
1989 |
Animal Care Assistant, Animal Care Facility, Department of Biology,
New York University, New York, NY. |
Semester/Yr. |
Course |
Location |
Position |
| Spring 2001 |
Introduction to Pathology |
UTMDACC |
Guest Lecturer |
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Summer 2000
|
Summer Program in Carcinogenesis |
UTMDACC |
Guest Lecturer |
| Spring 2000 |
Introduction to Pathology |
UTMDACC |
Guest Lecturer |
| Summer 1999 |
Summer Program in Carcinogenesis |
UTMDACC |
Guest Lecturer |
| Summer 1998 |
Summer Program in Carcinogenesis |
UTMDACC |
Guest Lecturer |
| Spring 1995 |
Field Biology and Elements of Ecology |
New York University |
Adjunct Professor |
| Fall 1994 |
Various Courses |
New York University |
Grader/Proctor |
| Spring 1994 |
Field Biology and Elements of Ecology |
New York University |
Adjunct Professor |
| Fall 1993 |
Principles of Biology I |
New York University |
Teaching Assistant |
| Spring 1993 |
Field Biology and Elements of Ecology |
New York University |
Adjunct Professor |
| Fall 1992 |
Genetics |
New York University |
Teaching Assistant |
| Spring 1993 |
Field Biology and Elements of Ecology |
New York University |
Adjunct Professor |
| Fall 1992 |
Genetics |
New York University |
Teaching Assistant |
| Spring 1992 |
Principles ofBiology II |
New York University |
Teaching Assistant |
| Spring 1992 |
Field Biology and Elements of Ecology |
New York University |
Adjunct Professor |
| Fall 1991 |
Tropical Field Ecology |
New York University |
Teaching Assistant |
| Fall 1991 |
Genetics |
New York University |
Teaching Assistant |
| Spring 1991 |
Various |
New York University |
Grader/Proctor |
| Fall 1990 |
Genetics |
New York University |
Teaching Assistant |
| Summer 1990 |
Genetics |
New York University |
Teaching Assistant |
| Spring 1990 |
Field Biology |
New York University |
Teaching Assistant |
| Fall 1989 |
Genetics |
New York University |
Teaching Assistant |
Awards and other Experience
| 2002 |
Invited Seminars, II International Symposium on Livebearing Fishes,
Queretaro, Mexico, and 29th Annual Meeting of the Texas Genetics Society
(South Padre Island, TX). |
2001 |
Invited Seminars U.T. Health Science Center, TX and N.Y.U. Medical
Center, Nelson Institute of Environmental Research. |
2001 |
Member of the Awards Committee, 28th Annual Meeting of the Texas Genetics
Society. |
1996-2001 |
Reviewed research manuscripts for Animal Genetics, Marine Biotechnology,
Genetics, and Gene. |
1991-2001 |
Supervised or assisted in supervision of nine undergraduate students
and one high school volunteer. Also worked closely with, and supervised
eight research technicians. |
2000 |
Invited Platform Speaker, Aquaria Models of Human Disease 1st Annual
Meeting, San Marcos, TX. |
2000 |
Oral presentation, 9th annual meeting of the Pan-American Society
for Pigment Cell Research, College Station, TX. |
2000 |
Invited Seminars, Texas State University | San Marcos, TX and Juniata
College, PA. |
1998 |
Invited Genetics Lecturer, Texas A&M University, TX. |
1997 |
Outstanding Young Investigator Award, 9th International Congress of
Genes, Gene Families, and Isozymes (Oral presentation). |
1991-1995 |
Participated in New York University student government, including
election to the Graduate Student Senate and serving as President of
the Biology Graduate Students ("Graduate Biology Group"). |
1994 |
Gladys Mateyko Award for Excellence in Biology, Department of Biology,
New York University, New York, NY. |
1993 |
Volunteer, assisted in extraction of geologic core samples Dr. Terry
Anne Maenza-Gmelch (supervisor), Tuxedo, N.Y. |
Professional Memberships and Interests
Grant and Contract Support
- Transposon Active Transgenic Xiphophorus (Ronald Walter, P.I., Drs.
S. Kazianis, Thomas Chen, Co-P.I.s, Dr. Perry Hackett, consultant).
R21 grant (2 year).
-
The Xiphophorus Genetic Stock Center, P40 RR017072 (Dr. R. Walter,
P.I., S. Kazianis, T. Tiersch Co-PIs). 2,039,734 (5 years).
- Genetic Determinants of Tumorigenesis, S/C P01 CA 75137 (Dr. R. Walter,
PI; $6,589,649 (5 years). S. Kazianis is PI of Project 3 (TxState component)
entitled Xiphophorus Gene Map Saturation for Identification of
Genes Regulating Tumor Development.
- Examination of the CDKN2X Gene in Xiphophorus Melanomas,
National Cancer Institute Post-Doctoral Training Fellowship 1 F32 CA76693-01,02,
Principal Investigator, 5/98-11/99, total $48,760.
- Institutional National Cancer Institute Post-Doctoral Training Fellowship,
5 T32CA09480-10,-11. Dr. Thomas Slaga, P.I. (U.T. MD Anderson Cancer
Center, SPRD), 8/95-8/97, total $ 43,500.
- The Xiphophorus melanoma receptor tyrosine kinase (XMRK) genes
in Xiphophorus variatus and their relationship to melanoma formation,
Dr. Frederick E.G. Valergakis Graduate Research Grant, Hellenic University
Club of New York, 6/92-6/93, total $1,250.
- Sigma Xi research society Grant-In-Aid of Research, 1990-91, total
$500.
Meeting Abstracts
A total of 30 abstracts have been submitted and presented at various
meetings and conferences.
Publications
- Schartl, A., Malitschek, B., Kazianis, S., Borowsky R. and
M. Schartl. 1995. Spontaneous melanoma formation in non-hybrid Xiphophorus.
Cancer Research, 55:159-165.
- Kazianis, S. and R. Borowsky. 1995. Stable association of a
pigmentation allele with an oncogene: non hybrid melanomas in Xiphophorus
variatus. Journal of Heredity. 86:199-203.
- Kazianis, S., Morizot, D., McEntire, B., Nairn, R., and R.
Borowsky. 1996. Genetic mapping in Xiphophorus hybrid fish: Assignment
of 43 AP-PCR and isozyme markers to multipoint linkage groups. Genome
Research. 6:280-289.
- Nairn, R., Kazianis, S., McEntire, B., Della Coletta, L., Walter,
R., and D. Morizot. 1996. A CDKN2-like polymorphism in Xiphophorus
linkage group V is associated with UV-B-induced melanoma formation in
platyfish-swordtail hybrids. Proceedings of the National Academy of
Sciences, U S A. 93: 13042-13047.
- Kazianis, S., Gan, L., Della Coletta, L., Santi, B., Morizot,
D.C., and R.S. Nairn. 1998. Cloning and comparative sequence analysis
of TP53 in Xiphophorus fish hybrid melanoma models. Gene. 212:
31-38.
- Kazianis, S., Gutbrod, H., Nairn, R., McEntire, B., Della Coletta,
L., Walter, R., Borowsky, R., Woodhead, A., Setlow, R., Schartl, M.,
and D. Morizot. 1998. Localization of a CDKN2 gene in linkage group
V of Xiphophorus fishes defines it as a candidate for the DIFF
tumor supressor. Genes Chromosomes and Cancer. 22:210-220.
- Morizot, D.C., McEntire, B.B., Della Coletta, L., Kazianis,
S., Schartl, M., and R.S. Nairn. 1998. Orthology and mapping of tyrosine
kinase genes in a Xiphophorus melanoma model. Molecular Carcinogenesis.
22: 150-157.
- McConnell, T.J., Godwin, U.B., Criscitiello, M.F., Nairn, R.S., Kazianis,
S., and D.C. Morizot. 1998. Identification and mapping of a novel major
histocompatability complex class II B gene in the platyfish (Xiphophorus
maculatus). Genetics. 149: 1921-1934.
- Morizot, D.C., Nairn, R.S., Walter, R.B., and S. Kazianis.
1998. Linkage map of Xiphophorus fishes. I.L.A.R. Journal. 39:
237-248.
- Williams, D., Kazianis, S., and R. Walter. 1998. Use of random
amplified polymorphic DNA (RAPD) for identification of largemouth bass
subspecies and their integrades. Transactions of the American Fisheries
Society. 127: 825-832.
- Kazianis, S., Morizot, D.C., Della Coletta, L., Johnston, D.A.,
Woolcock, B, Vielkind, J.R. and R.S. Nairn. 1999.
Comparative structure and characterization of a fish CDKN2 gene associated
with melanoma susceptibility. Oncogene. 18: 5088-5099.
- Kazianis, S., Morizot, D.C., Della Coletta, L., Osterndorff,
E., and R.S. Nairn. 2000. Hypomethylation and overexpression of a fish
CDKN2 gene in a hereditary melanoma model. Carcinogenesis. 21: 599-605.
- Kazianis, S., Gimenez-Conti, I., Trono D., Pedroza, A., Chovanec,
Lori, Morizot, D., Nairn, R., and R.Walter. 2001. Genetic analysis of
MNU-induced neoplasia within Xiphophorus hybrid fish. Marine
Biotechnology 3:S37-S43.
- Chen, J, Robinson, T, Kazianis, S, Della Coletta, L, Nairn,
R, and J. McCarrey. 2001. Assessment of p16CDKN2A involvement in a UV-induced
marsupial melanoma model. Molecular Carcinogenesis. 31:16-26.
- Gimenez-Conti, I., Woodhead, A. D., Harshbarger, J.C., Kazianis,
S., Setlow, R.B., Nairn, R.S., and R.B.Walter. 2001. A proposed classification
for Xiphophorus melanomas based on histopathology analysis. Marine
Biotechnology 3:S100-S106.
- Kazianis, S., Gimenez-Conti, I., Setlow, R.B., Woodhead, A.
D., Harshbarger, J.C., Trono D., Ledesma, M., Nairn, R.S., and R.B.Walter.
2001. MNU induction of neoplasia in a novel fish cancer model. Laboratory
Investigation 81:1191-1198.
- Morizot, D.C., Nairn, R.S., Simhambhatla, P, Della Coletta, L., Trono,
D., Chovanec, L., Walter, R.B., and Kazianis, S. 2001. The Xiphophorus
genetic linkage map: Beginnings of comparative gene mapping in fishes.
Marine Biotechnology 3:S153-161.
- Nairn, R.S., Kazianis, S., Della Coletta, L., Trono, D., Walter,
R.B., and D.C. Morizot. 2001. Genetic analysis of susceptibility to
UV carcinogenesis in Xiphophorus hybrid fish. Marine Biotechnology
3:S24-S36.
- Rosenthal, G.G., Morizot, D.C., Kazianis, S., Morris, M.R.,
Stephens, M. and M.J. Ryan. 2001. Dissolution of sexual signal complexes
in a swordtail hybrid zone. Copeia (Submitted).
Invited Reviews/Tributes
- Nairn, R., Morizot, D., Kazianis, S., Woodhead, A. and R. Setlow.
1996. Nonmammalian models for sunlight carcinogenesis: genetic analysis
of melanoma formation in Xiphophorus hybrid fish. Photochemistry
and Photobiology. 64: 440-448.
- Atz, J.W., and Kazianis, S. 2001. In appreciation of Klaus
D. Kallman. Marine Biotechnology 3:S3-S5.
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- Kazianis, S. and Walter, R.B., 2002. Use of platyfishes and
swordtails in biological research. Lab Animal 3:46-52.
Photographic Covers
Cover photographs for Genome Research (1996), Marine Biotechnology
(2001), Laboratory Investigation (2001).
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